Share on Facebook As computers have become mainstream appliances, they have found their way into virtually all aspects of human endeavors and medicine is no exception. Computers help physicians and medical researchers discover, test and apply medical techniques in virtually every hospital in the world. Furthermore, computer technology provides an infrastructure to allow for medical ideas and knowledge to be filed and shared globally with other medical professionals. Image generated by an MRI.
Our research is well-funded by grant support from federal sources such as the National Institutes of Health and from private foundations. Such support has resulted in high-quality publications in scientific journals as well as presentations at regional, national and international conferences.
Service Our faculty direct state-of-the-art cores such as the Flow Cytometry and Sorting.
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Our other shared resources comprise cutting-edge equipment and technology for Advanced Microscopy, —Omics Genomics, Epigenomics, Transcriptomics and Microbiome technology and Metabolic Profiling studies.
We welcome you to visit us to see our equipment and resources first-hand. They are appointed to national and international grant-review committees, hold offices in scientific societies, organize conferences and serve on government-appointed panels and scientific journal editorial boards.
They participate in teaching courses primarily for medical and graduate students, as well as for post-baccalaureate and physician assistant students. Infectious agents are discussed in relation to their morphology, biology, epidemiology and pathogenesis.
The role of the specific and nonspecific immune systems in defense against infection and disease, as well as in the causation of disease immunopathogenesisis emphasized.
A section of the course is devoted to special topics in infectious diseases. Modes of assessment include departmental written multiple choice examination and an assessment of participation in problem-solving exercises, case study discussions and computer simulated laboratory exercises.
Primary methods of instruction include lecture and small-group discussion. Topics on immune system dysregulation and consequences as related to disease and health are included.
Current topics of interest in immunology also are covered. Overall, students will gain an advanced understanding of the immune system. By the end of this course the student will demonstrate knowledge and understanding in: The scientific paper discussion will include Introduction, Materials and Methods, Results, Discussion and Bibliography.
One of the most important aspects of this course is to train the student to critique research and to improve the quality of their research by incorporating novel concepts and techniques.
Experimental Pathology PATH This course is designed to provide graduate students with a fundamental biomedical knowledge base in human pathology and an introduction to the study of the disease process.
Particular emphasis will be given to the etiology, pathogenesis and description of gross and microscopic pathologic patterns occurring during the progress and outcome of major human diseases and conditions.
Students will be introduced to the experimental approach of the development and subsequently effective treatment of certain diseases, through the description of animal models simulating related pathologies.
With the knowledge of normal histology, and by gaining familiarity of microscopic appearances through a hands-on experience at the lab small groups, students will develop observational and descriptive skills and ultimately deepen thier understanding of the underlying mechanisms of disease.
By the description of the experimental methodologies, including the murine models of various diseases, they will formulate the causative approach in the study of disease. Research Area Focus Groups The research interests of our faculty fall under the following main thematic groups.
Expand all Prakash Nagarkatti - Epigenetic regulation of inflammatory and autoimmune diseases, including multiple sclerosis and autoimmune hepatitis. Mitzi Nagarkatti - Effect of microbiome in inflammatory diseases such as colitis, obesity and cancer. Angela Murphy — Role of macrophage-induced inflammation in colon cancer Carole Oskeritzian — Targeting skin inflammation in atopic dermatitis Gregorio Gomez — Effect of resveratrol on IgE-dependent mast cell functions in allergies Dev Karan — Targeting inflammation-associated pathways in prostate cancer Jason Kubinak — Interaction of primary antibody deficiency and inflammation caused by host-microbiome dysbiosis Narendra Singh — Role of aryl hydrocarbon receptor in lupus, MS and diabetes Udai Singh — Mucosal inflammation and chemokines in colitis and cystitis Obesity, Metabolic Syndrome and Exercise Angela Murphy — Effect of exercise in obesity and metabolic disorders Reilly Enos — Cellular and molecular mechanisms in induction of obesity and metabolic syndrome.
Prakash Nagarkatti - Cannabinoid receptor antagonists in the treatment of obesity Mitzi Nagarkatti - Gut microbiome in obesity Udai Singh — Chemokines and chemokine receptors in obesity Allergies and Asthma Carole Oskeritzian — Role of mast cells and eosinophils in allergies including asthma and atopic dermatitis Gregorio Gomez — Adenosine in mediator release by mast cells in allergies Cancer Dev Karan — Development of vaccines against prostate-specific antigens for immunotherapy Lucia Pirisi-Creek — Mechanisms of progression of human papilloma virus infection-induced cervical cancer in patients and the effects of herceptin in breast cancer Swapan Ray — Use of chemoimmunotherapy in treatment of glioblastoma and neuroblastoma Carole Oskeritzian — Targeting Sphingosine-1 phosphate in macrophages and mast cells for cancer therapy.
Mitzi Nagarkatti — Role of microRNA in induction of apoptosis in tumor stem cells from neuroblastoma and melanoma Prakash Nagarkatti - Epigenetic regulation colon cancer by plant products Traci Testerman — H. Mitzi Nagarkatti — Effects of dietary supplements indoles, etc.
Gregorio Gomez — Effect of resveratrol on IgE-dependent mast cell functions in allergy Dev Karan — Mechanisms underlying dietary Withaferin-A modulation of inflammation associated with prostate cancer Narendra Singh — Therapeutic efficacy of resveratrol and other AhR ligands on MS, lupus and diabetes Udai Singh — Immune mechanisms of resveratrol-mediated amelioration of colitis and interstitial cystitis Infectious Diseases Traci Testerman — Pathogenesis and metabolic functions of H.
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Get excellent recommendation letters. Pathology, Microbiology and Immunology. We are primarily involved in teaching, research and service. Our research is well-funded by grant support from federal sources such as the National Institutes of Health and from private foundations.
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